Publications

Disrupted Maturation of Prefrontal Layer 5 Neuronal Circuits in an Alzheimer’s Mouse Model of Amyloid Deposition

Published in Neuroscience Bulletin, 2022

This paper investigates transgenic mutant forms of APP/PS1 overexpression in 5XFAD mouse models and their effects on early brain development.

Recommended citation: Chen, C., Wei, J., Ma, X. et al. Disrupted Maturation of Prefrontal Layer 5 Neuronal Circuits in an Alzheimer’s Mouse Model of Amyloid Deposition. Neurosci. Bull. (2022). https://doi.org/10.1007/s12264-022-00951-5

Early impairment of cortical circuit plasticity and connectivity in the 5XFAD Alzheimer’s disease mouse model

Published in Translational Psychiatry, 2022

This paper investigates the effects of overexpression of human amyloid precursor protein and presenilin 1 on tbe plasticity of early developing brain circuits.

Recommended citation: Chen, C., Ma, X., Wei, J. et al. Early impairment of cortical circuit plasticity and connectivity in the 5XFAD Alzheimer’s disease mouse model. Transl Psychiatry 12, 371 (2022). https://doi.org/10.1038/s41398-022-02132-4